L-Mesitran / Medical Grade Honey — Advanced Wound Care Solutions
DYNAMED is proud to partner with L-Mesitran as the authorised distributor of their medical-grade honey–based wound healing products in South Africa.
L-Mesitran proves to be the best Medical Grade Honey product to get rid of biofilms in wounds. This was published in the journal Antibiotics. The study at the University of Ghent shows that six different commercially available MGH-based wound care products are effective to prevent and remove biofilms.
L-Mesitran Soft demonstrates significantly stronger activity than the other products, because of its added components. The clinical efficacy of L-Mesitran Soft has also been supported in clinical cases of persistent biofilms without the need of using antibiotics.
Why Choose L-Mesitran via DYNAMED?
Expert local support — we provide training, clinical support, and on-the-ground logistics.
Regulatory compliance & quality assurance — we handle registration, importation, and quality control to ensure product integrity.
Complement to existing wound protocols — L-Mesitran can integrate with standard wound care (e.g. with foams, compression, negative pressure) to enhance outcomes.
Evidence-based choice — you bring a proven product with a robust research and clinical usage track record.
L-Mesitran Product Portfolio
Explore the full range of L-Mesitran Medical Grade Honey wound care products.
L-Mesitran Soft (Wound Gel)
Hydro-active gel with ~40% Medical Grade Honey, enriched with vitamins C & E and lanolin; suitable for acute and chronic wounds.
Learn more →L-Mesitran Ointment
Antibacterial ointment with ~48% Medical Grade Honey; maintains a moist wound environment and supports autolytic debridement.
Learn more →L-Mesitran Foam
Non-adherent polyurethane foam impregnated with L-Mesitran Soft; cushions, absorbs, and retains exudate.
Learn more →L-Mesitran Tulle
Non-adherent mesh/tulle dressing coated with L-Mesitran Soft; conforms to irregular wound geometries.
Learn more →L-Mesitran Border
Self-adhesive hydro-active dressing containing ~30% Medical Grade Honey; easy fixation for superficial wounds.
Learn more →L-Mesitran Hydro
Hydro-active antibacterial sheet containing L-Mesitran Soft; ideal for wounds with low to moderate exudate.
Learn more →L-Mesitran Active
Small hydro-active dressing with ~30% Medical Grade Honey; adheres where regular dressings won’t stay (e.g., blisters or joints).
Learn more →
Clinical & Application Highlights
L-Mesitran products support all phases of wound healing, from debridement/cleansing to epithelialization and remodeling.
They are effective against biofilms and local infections, even against some antibiotic-resistant organisms.
The dressings create a moist wound environment via osmotic activity, support autolysis of necrotic tissues, and enhance cell migration.
Dressings are designed for ease of use, minimal pain on removal, and less frequent changing (depending on wound exudate level).
L‑Mesitran Wound Care Protocol
Guidance matrix (no images) showing recommended L‑Mesitran dressings by wound bed appearance and exudate level. Always follow local clinical protocols.
| Wound type | Dry | Moderate exudate | Heavy exudate | |||
|---|---|---|---|---|---|---|
| Superficial | Deep | Superficial | Deep | Superficial | Deep | |
| Red wound protect · moist env · bacterial balance · stimulate epithelization |
TulleSoftHydroBorder |
Soft |
TulleSoftHydroBorderFoam |
SoftFoam |
SoftNetFoam |
SoftFoam |
| Yellow wound debride · remove bacteria · moist env · stimulate healing |
TulleSoftHydroBorder |
Soft |
TulleSoftHydroBorderFoam |
SoftFoam |
SoftNetFoam |
SoftFoam |
| Black wound cleanse · remove necrosis · reduce bacteria |
TulleSoftOintment |
OintmentSoft |
TulleOintmentFoam |
OintmentFoam |
OintmentNetFoam |
OintmentSoft |
| Post‑operative wound improve healing · reduce scarring · prevent infection |
TulleOintment |
Soft |
TulleOintment |
Soft |
TulleSoft |
Ointment |
This chart is a simplified, image‑free representation for web display. Product choices may vary with assessment, location, and protocol. Consider patient comfort, exudate levels, and dressing change frequency when selecting between Soft, Ointment, Tulle/Net, Hydro, Border, and Foam.
L-Mesitran Frequently Asked Questions
What is L-Mesitran?
L-Mesitran is the pioneering brand of wound care products based on medical grade honey. We aspire to deliver high quality products for fast and efficient wound healing.
The first product, L-Mesitran Ointment, has been approved in Europe since 2002. The products are CE approved for the European market, FDA approved for the market in the USA and further they are approved in over fifty countries worldwide with differentiated registrations. The products are used in hospitals, nursery homes, domestic care and of course the consumer at home. All of the products are provided with a leaflet including specific instructions for use for each product alone.
Why can’t I just buy honey in the supermarket and apply it straight onto the wound?
There are a number of reasons why you should not apply supermarket honey on wounds:
– Honey from the supermarket is not indicated or licensed to be used as a medical device.
– Honey frequently contains a bacteria (clostridium botulinum) which causes wound botulism and can be fatal.
– Honey can contain all sorts of pollutants that are not dangerous when digested by healthy human beings, but are unwanted in a wound. For example, heavy metals, pesticides and herbicides.
Not all types of honey are the same and can vary in their therapeutic effect.
Our products are licensed medical devices for wound management. The production and selection of the honey is done by qualified persons and the production processes are validated and audited by medical device authorities (CE and FDA).
You can be sure L-Mesitran is safe and effective to use.
What is the origin of the honey used in your products?
The honey we use is certified organic honey, harvested conform strict guidelines. For example, the honey has to be free from antibiotics and may not contain herbicide or pesticides, heavy metals or other pollutants. We use several floral species and the honey is tested to meet our medical grade standard. Furthermore, the honey is irradiated by gamma radiation to make sure all pollutants, that might cause an adverse reaction, are killed.
Can L-Mesitran cause pain?
In some cases, L-Mesitran can cause pain. It has been reported to cause pain when using L-Mesitran Ointment and sometimes L-Mesitran Soft. The pain can be caused due to the osmotic action of the sugars in the honey and the change of pH in the wound bed when applying the products.
The pain usually subsides after a short while. When this is not the case, you should consult with a physician and perhaps use a painkiller. Another method is to wet the gauze covering the wound with purified water. This will diminish the osmotic action and can provide relieve.
Why does the surrounding tissue of the wound turn reddish after the L-Mesitran is applied?
L-Mesitran activates the wound healing process. Within this natural process, an inflammatory phase is inevitable. This phase is crucial in order to cleanse the wound of dead tissue and microorganisms. This inflammatory phase is characterized by the fact that the blood vessels surrounding the wound supply more blood to the wound area.
Where can I buy L-Mesitran products?
Find your distributor here

